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• December 18, 2024
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We surmise that results obtained from the experiments described in this section cannot serve to understand the role of I_NaL in arrhythmogenesis.

1. Van Driessche W, Lindemann B: Amount reliance of currents thanks to single sodium-choosy skin pores into the frog body. Characteristics. 1979; 282 (5738): 519-520 PubMed Abstract | Writer Complete Text

It means brand new good conclusions submit from this manuscript try not justified and i also never agree the fresh manuscript in this form

The brand new article writers has explained a number of the inquiries I increased during the my earlier in the day remark. Unfortuitously, all of the significant dilemmas haven’t been handled through this revise. While i made in my earlier opinion, I consider it unrealistic that every those individuals situations are going to be fixed just because of the several additional sentences. As an alternative there are certain fundamental concerns on experimental design and you can, really vitally, with the data.

This means this new solid findings put forward by this manuscript is not justified and i also you should never agree the manuscript within this form

The article authors features clarified a number of the issues I raised inside my personal earlier in the day remark. Unfortunately, the big problems have not been treated from this inform. Once i made in my personal earlier in the day comment, We consider they unlikely that the individuals products are going to be repaired simply by the several added paragraphs. Alternatively you may still find certain practical issues towards fresh design and you may, extremely vitally, towards study.

• The most effective issue is whenever I followed the fresh new dysfunction off the methods in the previous variation it actually was you can to decode, with almost best accuracy, people random stimulus names We chose. Select for types of it reanalysis. It doesn’t matter if i pretend that the genuine stimuli seemed during the an afterwards time or are constantly switching between code and you will quiet, the fresh new decoding is always next to finest. This can be indicative the decryption has nothing to do to the real stimulus heard from the Transmitter it is opportunistically exploiting additional enjoys in the data. Brand new manage write my essay for me best website research the new writers did, treating the newest stimulus labels, usually do not address this dilemma because it is affected with equivalent state. Essentially, what the classifier try presumably playing with is the time who’s got introduced since recording come.
• The explanation for this is exactly presumably your article writers utilized non-separate research getting training and you may assessment. And in case I understand precisely (get a hold of section 3), haphazard sampling half of data products away from an enthusiastic EEG shade commonly separate study. Repeating the research 5 times – the new control data the people did – isn’t an acceptable treatment for target it concern. Randomly looking examples regarding a time show who has sluggish changes (including the sluggish wave activity one to allegedly dominates these recordings below these circumstances) have a tendency to usually have strong temporal correlations. See TemporalCorrelations.jpg in for 2D occurrence histograms and you will a relationship matrix indicating so it.
• As the revised strategies area will bring more detail today, they still is unclear about just what investigation were utilized. Traditional class data statement what study have (common articles throughout the data matrix) and you may exactly what observations (usual rows) were utilized. Anything will be an element however, usually this really is the fresh more EEG avenues otherwise fMRI voxels etcetera. Observations usually are go out products. Here I guess the new article writers transformed the fresh intense samples into the an excellent additional room playing with principal parts analysis. That isn’t said if your dimensionality is actually faster making use of the eigenvalues. In either case, I suppose the knowledge samples (collected from the 128 Hz) were next used while the observations as well as the EEG avenues switched from the PCA were utilized due to the fact provides. The new stimuli brands was basically tasked as the On the or Out-of for each and every decide to try. A set of 50% from trials (and you can labels) was then picked randomly for training, in addition to other people was used getting investigations. Is it right?